The Nesbitt's Fruit Products Company was founded in 1924, named after its founder Hugh S. Nesbitt. The Nesbitt's brand debuted in 1927, initially as part of the company's line of soda fountain products. Nesbitt's began bottling Nesbitt's orange and several other flavors in the late 1930s, putting it in direct competition with established market-leader Orange Crush. Nesbitt's became the US market leader of orange soda pop during the late 1940s and 1950s, wit advertisements featuring a then-unknown model named Marilyn Monroe and proclaiming itself to be the "Largest selling bottled orange drink in the world".
Nesbitt's own brand of orange beverage was surpassed in popularity by Fanta in the late 1960s and then faded in popularity.